Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.47 |
| ▸ | CDK2 | P24941 | 4/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159560 | 0.83 | PAK1 (0.41) | — | |
| SCHEMBL9160663 | 0.80 | — | — | |
| SCHEMBL6754891 | 0.75 | MEN1 (0.51) | MAPT | |
| SCHEMBL9373248 | 0.71 | MEN1 (0.46) | MAPT | |
| SCHEMBL9160789 | 0.70 | MEN1 (0.45) | MAPT | |
| SCHEMBL9374375 | 0.69 | — | — | |
| SCHEMBL9375755 | 0.69 | — | — | |
| SCHEMBL9370814 | 0.66 | — | — | |
| SCHEMBL22450141 | 0.65 | MEN1 (0.61) | ALDH1A1MAPT | |
| SCHEMBL28298919 | 0.65 | KMT2A (0.58) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478830-A | Pyrazolo pyrimidines; inhibitors of acyl-coenzyme A and cholesterol acyltransferase; antihypercholesterolemic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-12-26 | — | — | US | disclosed |