Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159680 | 0.95 | ALOX5 (0.39) | ALOX5PARP14MAOBP2RY14KDM4E | |
| SCHEMBL9159665 | 0.91 | ALOX5 (0.37) | ALOX5MAOB | |
| SCHEMBL9160050 | 0.89 | ALOX5 (0.41) | ALOX5PARP14MAOB | |
| SCHEMBL9254545 | 0.81 | MAOB (0.61) | MAOBALDH1A1TDP1 | |
| SCHEMBL9161622 | 0.80 | MAOB (0.39) | ALOX5MAOBALDH1A1HSD17B10 | |
| SCHEMBL9154816 | 0.79 | MAOB (0.38) | ALOX5MAOBP2RY14ALDH1A1 | |
| SCHEMBL9158135 | 0.79 | ALOX5 (0.42) | ALOX5MAOBALDH1A1 | |
| SCHEMBL9161437 | 0.79 | GRM4 (0.39) | ALOX5 | |
| SCHEMBL9160895 | 0.78 | MAOB (0.38) | ALOX5MAOBALDH1A1 | |
| SCHEMBL9154676 | 0.77 | GRM4 (0.38) | ALOX5PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410054-A | Heteroaryl quinolines as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1995-04-25 | — | — | US | disclosed |