Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267747 | 0.90 | MAOB (0.48) | MAOBNPC1RAB9AMAOACASP3 | |
| SCHEMBL9258559 | 0.90 | MAOB (0.48) | MAOBNPC1RAB9AMAOACASP3 | |
| SCHEMBL9265290 | 0.90 | MAOB (0.63) | MAOBALDH1A1HPGDUSP2NPC1 | |
| SCHEMBL9259277 | 0.88 | RAB9A (0.61) | MAOBNPC1RAB9AMAOACASP3 | |
| SCHEMBL9267165 | 0.85 | KMT2A (0.51) | MAOBALDH1A1HPGDNPC1CYP2C9 | |
| SCHEMBL9263722 | 0.84 | NPC1 (0.58) | MAOBNPC1RAB9AMAOAMEN1 | |
| SCHEMBL9161622 | 0.84 | MAOB (0.39) | MAOBALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL9158135 | 0.83 | ALOX5 (0.42) | MAOBALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL9154816 | 0.83 | MAOB (0.38) | MAOBALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL9263552 | 0.83 | MAOB (0.47) | MAOBNPC1RAB9AMAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424320-A | Antihistamine, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-13 | — | — | US | disclosed |
| US-5360815-A | Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1994-11-01 | — | — | US | disclosed |