SCHEMBL9154795

SCHEMBL9154795

CN1C=CCN(c2ccccc2)N1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
G6PD P11413 2/20 0.41
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX5 P09917 7/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
HTR3E A5X5Y0 1/20 0.31
HTR3B O95264 1/20 0.31
ADRB1 P08588 1/20 0.31
HTR3A P46098 1/20 0.31
HTR3D Q70Z44 1/20 0.31
HTR3C Q8WXA8 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10805291 0.83 ALOX5 (0.40) L3MBTL1ALOX5ADRB1
SCHEMBL3192879 0.78 CFTR (0.39) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL11420099 0.69 CYP1A2 (0.35) G6PDGAAL3MBTL1ALOX15ALOX12
SCHEMBL44774 0.67 ALOX5 (0.39) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL10955920 0.66 LMNA (0.44) GAA
SCHEMBL94012 0.65 GSK3A (0.34) ALOX15PTGS2GSK3AGSK3BSIGMAR1
SCHEMBL94011 0.65 GSK3A (0.39) G6PDGAAL3MBTL1ALOX15PTGS1
SCHEMBL15151279 0.65 ALOX5 (0.50) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL17577923 0.63 GAA (0.42) G6PDGAAL3MBTL1ALOX5
SCHEMBL17577892 0.62 MAOB (0.42) G6PDGAAL3MBTL1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5380394-A Image forming apparatus KABUSHIKI KAISHA TOSHIBA (JP) 1995-01-10 US disclosed