SCHEMBL9154803

SCHEMBL9154803

NCCCC1CCCCC1O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA4 P22748 2/20 0.56
SIGMAR1 Q99720 1/20 0.40
SLC18A3 Q16572 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5034130 0.86 CA1 (0.60) CA1CA2CA4SIGMAR1SLC18A3
SCHEMBL5037292 0.86 CA1 (0.60) CA1CA2CA4SIGMAR1SLC18A3
SCHEMBL23004872 0.86 CA1 (0.60) CA1CA2CA4SIGMAR1SLC18A3
SCHEMBL1615265 0.83 SIGMAR1 (0.48) CA1CA2CA4SIGMAR1
SCHEMBL16705451 0.79 CA1 (0.39) CA1CA2CA4SIGMAR1
SCHEMBL1160732 0.79 CA1 (0.58) CA1CA2CA4SLC18A3
SCHEMBL31645807 0.78 CA1 (0.62) CA1CA2CA4SLC18A3
SCHEMBL1160724 0.78 CA1 (0.62) CA1CA2CA4SLC18A3
SCHEMBL31645217 0.78 CA1 (0.62) CA1CA2CA4SLC18A3
SCHEMBL4806965 0.77 CA1 (0.56) CA1CA2CA4SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449111-B1 Process for preparing 2-(3-aminopropyl)-cycloalkylamines BASF AG (DE) 1995-02-15 EP disclosed
US-5239120-A PREPARATION OF 2-(3-AMINOPROPYL)-CYCLOALKYLAMINES BASF AKTIENGESELLSCHAFT (DE) 1993-08-24 US disclosed
EP-0449111-A1 Process for preparing 2-(3-aminopropyl)-cycloalkylamines BASF Aktiengesellschaft (DE) 1991-10-02 EP disclosed
EP-0000016-B1 PROCESS FOR THE PREPARATION OF ALLOPHANATES-SUBSTITUTED POLYISOCYANATES AND THEIR USE IN THE MANUFACTURE OF POLYURETHANE PRODUCTS BAYER AG (DE) 1980-07-23 EP disclosed
US-4177342-A FROM CARBAMATE(URETHANE)-CONTAINING ALCOHOLS AND POLYISOCYANATES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-04 US disclosed
EP-0000016-A1 Process for the preparation of allophanates-substituted polyisocyanates and their use in the manufacture of polyurethane products BAYER AG (DE) 1978-12-20 EP disclosed
US-4124569-A LACQUERS BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed