SCHEMBL5034130

SCHEMBL5034130

NCC[C@@H]1CCCC[C@H]1O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
CA4 P22748 2/20 0.60
SIGMAR1 Q99720 1/20 0.33
SLC18A3 Q16572 3/20 0.33
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
TSHR P16473 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23004872 1.00 CA1 (0.60) CA1CA2CA4SIGMAR1SLC18A3
SCHEMBL5037292 1.00 CA1 (0.60) CA1CA2CA4SIGMAR1SLC18A3
SCHEMBL9154803 0.86 CA1 (0.56) CA1CA2CA4SIGMAR1SLC18A3
SCHEMBL13495040 0.81 CA1 (0.40) CA1CA2CA4
SCHEMBL201965 0.81 SIGMAR1 (0.40) CA1CA2CA4SIGMAR1NOS3
SCHEMBL862022 0.79
SCHEMBL6443728 0.79
SCHEMBL1413431 0.79
SCHEMBL1413545 0.79
SCHEMBL3975908 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705275-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2026-03-11 EP disclosed
US-20240417370-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2024-12-19 US disclosed
WO-2024233387-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2024-11-14 WO disclosed
EP-1450796-B1 BENZOTHIAZOLE DERIVATIVES HOFFMANN LA ROCHE (CH) 2008-04-09 EP disclosed
EP-1680666-A4 DETECTING HUMAN ANTI-THERAPEUTIC ANTIBODIES MONOGRAM BIOSCIENCES INC (US) 2008-03-26 EP disclosed
EP-1680666-A2 DETECTING HUMAN ANTI-THERAPEUTIC ANTIBODIES Monogram Biosciences, Inc. (US) 2006-07-19 EP disclosed
WO-2005045058-A2 DETECTING HUMAN ANTI-THERAPEUTIC ANTIBODIES MONOGRAM BIOSCIENCES, INC. (US) 2005-05-19 WO disclosed
US-6596718-B1 A compound of formula I has a good affinity to the A2A receptor and is useful for the treatment of diseases mediated by this receptor. HOFFMANN-LA ROCHE INC. 2003-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240417370-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS LIPA, PHOSPHO1, LIPC CA1 2767/4885CA2 3487/4885CA4 4019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.