Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13266307 | 0.89 | SIGMAR1 (0.39) | SIGMAR1NFKB1 | |
| SCHEMBL23742068 | 0.89 | SIGMAR1 (0.62) | SIGMAR1NFKB1CA1CA2CA4 | |
| SCHEMBL22260597 | 0.87 | SIGMAR1 (0.67) | SIGMAR1NFKB1CA1CA2CA4 | |
| SCHEMBL7241863 | 0.85 | SIGMAR1 (0.41) | SIGMAR1NOS3NOS1NOS2 | |
| SCHEMBL9154803 | 0.83 | CA1 (0.56) | SIGMAR1CA1CA2CA4 | |
| SCHEMBL18468277 | 0.83 | SIGMAR1 (0.40) | SIGMAR1CA1CA2CA4EPHX1 | |
| SCHEMBL201965 | 0.81 | SIGMAR1 (0.40) | SIGMAR1CA1CA2CA4NOS3 | |
| SCHEMBL9151545 | 0.79 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL11993678 | 0.79 | SIGMAR1 (0.52) | SIGMAR1CA1CA2CA4CA12 | |
| SCHEMBL25639624 | 0.79 | SIGMAR1 (0.52) | SIGMAR1CA1CA2CA4DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338065-B2 | Electrophotographic photoreceptor and image forming apparatus provided with the same | SHARP KABUSHIKI KAISHA (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110085823-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2011-04-14 | — | — | US | disclosed |