Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153423 | 0.80 | CYP2D6 (0.40) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL31572047 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL49805 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL9153395 | 0.76 | LMNA (0.44) | HIF1AL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10522680 | 0.75 | CYP3A4 (0.72) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL11347493 | 0.75 | TSHR (0.72) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL2534270 | 0.74 | ALDH1A1 (0.69) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL28983287 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL15576239 | 0.73 | SMN1; SMN2 (0.67) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 | |
| Glycolic Acid SCHEMBL8595822 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HIF1AL3MBTL1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363034-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1995-01-04 | — | — | EP | disclosed |
| EP-0605404-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | disclosed |
| US-5212313-A | For polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-18 | — | — | US | disclosed |
| US-5183888-A | Reacting a phenyl tartronic acid with a dihydrobenzofuran, oxidizing, to get dihydrobenzodifuran | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |