Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153428 | 0.79 | POLB (0.53) | MAPTEPHX2HTTFFAR1CA1 | |
| Oxalic Acid SCHEMBL9716123 | 0.78 | LMNA (0.55) | LMNAMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL9153014 | 0.77 | CA12 (0.47) | LMNAEPHX2NR1H4FFAR1CA1 | |
| Acetic Acid SCHEMBL29202236 | 0.76 | EPHX2 (0.52) | LMNAEPHX2HTTL3MBTL1FFAR1 | |
| SCHEMBL18156890 | 0.76 | ADRA2A (0.46) | LMNAMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL8434483 | 0.76 | VDR (0.49) | LMNAMAPTNR1H4HTTMEN1 | |
| SCHEMBL9154932 | 0.76 | ALDH1A1 (0.58) | CYP2C9CYP2D6HIF1AEPHX2NR1H4 | |
| SCHEMBL18171766 | 0.72 | LMNA (0.50) | LMNAMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL28670574 | 0.72 | LMNA (0.50) | LMNAMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL455156 | 0.72 | HCAR3 (0.55) | LMNAMAPTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363034-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1995-01-04 | — | — | EP | disclosed |
| EP-0605404-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | disclosed |
| US-5212313-A | For polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-18 | — | — | US | disclosed |
| US-5183888-A | Reacting a phenyl tartronic acid with a dihydrobenzofuran, oxidizing, to get dihydrobenzodifuran | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |