SCHEMBL915502

SCHEMBL915502

O=P(O)(O)Cc1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 7/20 0.50
PGK2 P07205 7/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 1/20 0.50
PTPN1 P18031 1/20 0.50
ACP3 P15309 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29616518 1.00 PGK1 (0.50) PGK1PGK2CYP1A2CYP2A6PTPN1
SCHEMBL9170574 0.92 PGK1 (0.50) PGK1PGK2ACP3
SCHEMBL9169463 0.90 PGK1 (0.48) PGK1PGK2PTPN1ACP3
SCHEMBL21585529 0.84 CA12 (0.44) PGK1PGK2ACP3
SCHEMBL2867017 0.83 CTRC (0.47) PGK1PGK2PTPN1ACP3
SCHEMBL21585534 0.82 CA12 (0.43) PGK1PGK2PTPN1ACP3
SCHEMBL148993 0.82 PTPN1 (0.45) CYP1A2CYP2A6PTPN1
SCHEMBL5080653 0.81 CYP2A6 (0.42) PGK1PGK2CYP2A6ACP3
SCHEMBL11891943 0.80 CYP1A2 (0.50) CYP1A2CYP2A6PTPN1
SCHEMBL13486393 0.80 CYP1A2 (0.55) CYP1A2CYP2A6PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500417-A ANTIARTHRITIC THE UPJOHN COMPANY (US) 1996-03-19 US claimed
EP-0661978-A1 ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS PHARMACIA & UPJOHN COMPANY (US) 1995-07-12 EP claimed
WO-1994007501-A1 ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1994-04-14 WO claimed
US-20250298333-A1 POLYESTER RESIN COMPOSITION, ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, DEVELOPER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2025-09-25 US disclosed
WO-2024020507-A2 ORGANOPHOSPHOROUS COMPOUNDS AND USES THEREOF JAL THERAPEUTICS, LLC (US) 2024-01-25 WO disclosed
US-11329241-B2 Exciton-blocking treatments for buffer layers in organic photovoltaics THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-05-10 US disclosed
EP-2484714-B1 POLYESTER FILM FOR PROTECTION OF BACK SURFACES OF SOLAR CELLS TOYO BOSEKI (JP) 2018-05-02 EP disclosed
US-9902712-B2 Nitrogenous heterocyclic derivatives and their application in drugs SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-02-27 US disclosed
EP-3083584-B1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN THE TREATMENT OF TISSUE FIBROSIS SUNSHINE LAKE PHARMA CO LTD (CN) 2018-02-21 EP disclosed
US-9640689-B2 Polyester film for the protection of back surfaces of solar cells TOYO BOSEKI KABUSHIKI KAISHA (JP) 2017-05-02 US disclosed
US-20160355501-A1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS SUNSHINE LAKE PHARMA CO., LTD. (CN) 2016-12-08 US disclosed
EP-0816354-A1 Process for preparing and stabilisation of aliphatic six-membered cyclic carbonates BAYER AG (DE) 1998-01-07 EP disclosed
US-5593980-A ANTIARTHRITIC AGENTS FOR ADMINISTERING THE UPJOHN COMPANY (US) 1997-01-14 US disclosed
US-5500417-A ANTIARTHRITIC THE UPJOHN COMPANY (US) 1996-03-19 US disclosed
EP-0661978-A1 ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS PHARMACIA & UPJOHN COMPANY (US) 1995-07-12 EP disclosed
WO-1994007501-A1 ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1994-04-14 WO disclosed
US-4960841-A REACTING A PREPOLYMER WITH A MIXTURE OF A DIHALODIPHENYL-SULFONE OR A HALOGENATED AROMATIC COMPOUND AND A SULFIDIZATION AGENT IN A POLAR SOLVENT DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-10-02 US disclosed
EP-0023314-B1 PROCESS FOR PREPARING POLY(ARYLENE SULFIDES) BAYER AG (DE) 1983-07-20 EP disclosed
US-4331801-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1982-05-25 US disclosed
EP-0023314-A1 Process for preparing poly(arylene sulfides) BAYER AG (DE) 1981-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160355501-A1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS TNNC1, IAPP, TNNI3 PGK1 2004/4885PGK2 2681/4885CYP1A2 2780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.