Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463508 | 0.88 | FFAR1 (0.46) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL7363405 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL7294570 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL9115691 | 0.81 | TNF (0.58) | ALDH1A1TNFPOLBKMT2AACHE | |
| SCHEMBL30147220 | 0.81 | ACHE (0.53) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL8355373 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL8355366 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL8355369 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL9456558 | 0.80 | PDE4B (0.55) | ALDH1A1HTTKDM4ELMNAMAPT | |
| SCHEMBL21632014 | 0.79 | KMT2A (0.61) | LMNAFFAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5444083-A | DOPAMINE AGONIST FOR TREATING OR PREVENTION OF HYPERTENSION OR HEART FAILURE | EISAI CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |