Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 9/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294570 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL9155153 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL30530004 | 0.86 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7363289 | 0.86 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4683616 | 0.80 | HTT (0.43) | ALDH1A1LMNAMAPTHTTTNF | |
| SCHEMBL7744741 | 0.80 | KMT2A (0.47) | ALDH1A1KDM4EMAPTHTTPDE4A | |
| SCHEMBL30147220 | 0.80 | ACHE (0.53) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL7366317 | 0.79 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8771052 | 0.79 | TNF (0.56) | ALDH1A1TNFPDE4APDE4BPDE4C | |
| SCHEMBL31467205 | 0.79 | HTT (0.48) | ALDH1A1KDM4ELMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584208-A4 | — | — | 1994-03-23 | — | — | EP | disclosed |
| EP-0584208-A1 | PYRROLIDINONES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992019594-A1 | PYRROLIDINONES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |