Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157731 | 0.96 | KMT2A (0.50) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL29063256 | 0.92 | EGFR (0.56) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9155520 | 0.83 | EGFR (0.55) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9766046 | 0.83 | L3MBTL1 (0.56) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9160532 | 0.80 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL1358575 | 0.80 | CYP1A2 (0.76) | KMT2AMEN1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9158331 | 0.79 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL1253013 | 0.77 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL9156334 | 0.77 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL29443924 | 0.77 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |