Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152814 | 0.93 | ACHE (0.46) | ACHEAGTR1AGTR2 | |
| SCHEMBL9150286 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9156524 | 0.85 | ACHE (0.45) | ACHEAGTR1AGTR2 | |
| SCHEMBL9149816 | 0.85 | ACHE (0.45) | ACHEAGTR1AGTR2 | |
| SCHEMBL9151246 | 0.84 | ACHE (0.51) | ACHEAGTR1AGTR2 | |
| SCHEMBL9538260 | 0.83 | ACHE (0.44) | ACHEAGTR1AGTR2 | |
| SCHEMBL9154093 | 0.83 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9154503 | 0.82 | ACHE (0.46) | ACHEAGTR1AGTR2 | |
| SCHEMBL9157026 | 0.81 | ACHE (0.46) | ACHEAGTR1AGTR2 | |
| SCHEMBL9156798 | 0.81 | ACHE (0.48) | ACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389659-A | Hypotensive agents | GLAXO GROUP LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| WO-1993005025-A1 | C-LINKED PYRAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-03-18 | — | — | WO | disclosed |