SCHEMBL9155264

SCHEMBL9155264

Nc1cc(S(=O)(=O)O)ccc1Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.59
MAPT P10636 7/20 0.59
GAA P10253 7/20 0.59
KDM4E B2RXH2 6/20 0.59
TDP1 Q9NUW8 4/20 0.59
CASP6 P55212 3/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
POLB P06746 2/20 0.59
NSD2 O96028 2/20 0.59
APEX1 P27695 1/20 0.59
APOBEC3A P31941 1/20 0.59
RECQL P46063 1/20 0.59
APOBEC3G Q9HC16 1/20 0.59
HSD17B10 Q99714 4/20 0.58
SNCA P37840 2/20 0.58
HPGD P15428 2/20 0.58
THRB P10828 1/20 0.58
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
GFER P55789 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11335315 0.87 RAPGEF4 (0.62) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL11792993 0.87 MAPT (0.58) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL15646797 0.83 KMT2A (0.58) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL10720084 0.81 RAPGEF4 (0.62) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL10721756 0.80 ALDH1A1 (0.56) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL11798698 0.79 LMNA (0.57) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL7890122 0.79 SNCA (0.59) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL27658915 0.78 GAA (0.57) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL22683201 0.78 RAPGEF4 (0.50) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL21589351 0.78 ALDH1A1 (0.58) ALDH1A1MAPTGAAKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241415-B1 Acid tin-(II)-containing electrolyte SANDOZ AG (CH) 1995-03-08 EP claimed
US-5312541-A Improvements in processes for coloring anodized aluminum and/or aluminum alloys SANDOZ LTD. (CH) 1994-05-17 US claimed
EP-0241415-B1 Acid tin-(II)-containing electrolyte SANDOZ AG (CH) 1995-03-08 EP disclosed
US-5312541-A Improvements in processes for coloring anodized aluminum and/or aluminum alloys SANDOZ LTD. (CH) 1994-05-17 US disclosed
US-5286809-A Glass fiber reinforced polyamide 6, polyphenylene sulfide grated with sulfonaphthalene diacid anhydride BAYER AG (DE) 1994-02-15 US disclosed
EP-0492246-A2 Thermoplastic moulding compositions BAYER AG (DE) 1992-07-01 EP disclosed
US-5086129-A POLYARYLENE SULPHIDE MODIFIED WITH ARYL SULFONIC ACID CONTAINING AMINO OR HYDROXYL GROUP BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0218131-B1 WATER SOLUBLE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP disclosed
US-4902786-A Phenylazonaphthol or naphthylazonaphthol compounds containing a fibre-reactive aminophenylamino-substituted halogen-s-triazinylamino group and a fibre-reactive group of the vinylsulfone series, suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-20 US disclosed
US-4775746-A Water-soluble monoazo compounds containing a fiber-reactive group of the vinylsulfone series and having a sulfonaphthol coupling component with a phenylaminotriazinylamino substituent, suitable as dyestuffs HOECHST AKTIENGESELLSHAFT (DE) 1988-10-04 US disclosed
US-4757136-A Water-soluble Azo compounds containing fiber-reactive groups and having a sulfo-naphthol coupling component with a triazinylamino substituent suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-12 US disclosed
US-4740592-A Water-soluble azo compounds containing fiber-reactive groups and having a sulfo-naphthal coupling component with a triazinylamino substituent suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-26 US disclosed
EP-0241415-A1 Acid tin-(II)-containing electrolyte SANDOZ AG (CH) 1987-10-14 EP disclosed
EP-0218131-A1 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-15 EP disclosed