Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155260 | 1.00 | PRMT6 (0.45) | PRMT6P2RY12P2RY1ADORA1 | |
| SCHEMBL17860572 | 0.93 | POLB (0.46) | ADORA1 | |
| SCHEMBL9295059 | 0.93 | POLB (0.46) | ADORA1 | |
| SCHEMBL18927158 | 0.93 | POLB (0.46) | ADORA1 | |
| SCHEMBL9703679 | 0.93 | POLB (0.46) | ADORA1 | |
| SCHEMBL25382491 | 0.92 | PRMT6 (0.40) | PRMT6P2RY12P2RY1 | |
| SCHEMBL30197028 | 0.91 | P2RY12 (0.43) | PRMT6P2RY12P2RY1 | |
| SCHEMBL8958832 | 0.85 | POLB (0.44) | ADORA1 | |
| SCHEMBL17911711 | 0.85 | TYMP (0.45) | PRMT6P2RY12 | |
| SCHEMBL21465199 | 0.84 | SLC29A1 (0.45) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470967-A | Hybridization probes to detect nucleic acid sequences | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0517796-B1 | OLIGONUCLEOTIDE ANALOGS | DU PONT MERCK PHARMA (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0517796-A1 | OLIGONUCLEOTIDE ANALOGS. | DU PONT (US) | 1992-12-16 | — | — | EP | disclosed |
| WO-1991015500-A1 | OLIGONUCLEOTIDE ANALOGS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-17 | — | — | WO | disclosed |