SCHEMBL30197028

SCHEMBL30197028

CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)C[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 5/20 0.43
P2RY1 P47900 2/20 0.42
PRMT6 Q96LA8 1/20 0.41
P2RY2 P41231 1/20 0.41
P2RY6 Q15077 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9703679 0.92 POLB (0.46)
SCHEMBL9295059 0.92 POLB (0.46)
SCHEMBL18927158 0.92 POLB (0.46)
SCHEMBL17860572 0.92 POLB (0.46)
SCHEMBL24823137 0.92 P2RY12 (0.42) P2RY12P2RY1PRMT6P2RY2P2RY6
SCHEMBL31195761 0.92 P2RY12 (0.42) P2RY12P2RY1PRMT6P2RY2P2RY6
SCHEMBL9155270 0.91 PRMT6 (0.45) P2RY12P2RY1PRMT6
SCHEMBL9155260 0.91 PRMT6 (0.45) P2RY12P2RY1PRMT6
SCHEMBL29461518 0.91 P2RY12 (0.48) P2RY12P2RY1P2RY2P2RY6
SCHEMBL3822223 0.91 P2RY12 (0.48) P2RY12P2RY1P2RY2P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111748550-B Method for labeling nucleic acid 国立大学法人九州大学 2023-11-24 CN disclosed
US-11499178-B2 Labeling method for nucleic acid KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11499178-B2 Labeling method for nucleic acid DNTT, RNMT, RNGTT P2RY12 4535/4885P2RY1 4291/4885PRMT6 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.