SCHEMBL9155272

SCHEMBL9155272

CC1CC(C)(C)N(CCN2c3ccccc3C(C)CC2(C)C)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
TSHR P16473 1/20 0.41
MAPT P10636 5/20 0.39
ALDH1A1 P00352 4/20 0.39
NOTUM Q6P988 1/20 0.39
NPSR1 Q6W5P4 3/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GPR3 P46089 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HRH1 P35367 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 2/20 0.34
HTT P42858 1/20 0.34
ROCK1 Q13464 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11428861 0.92 CRHBP (0.45) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL11431643 0.91 CRHBP (0.44) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL11419734 0.91 CRHBP (0.47) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL8942349 0.91 CRHBP (0.47) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL9636461 0.89 CRHBP (0.43) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL3975558 0.88 CRHBP (0.47) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL10886763 0.88 CRHBP (0.43) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL11417208 0.88 CRHBP (0.43) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL11431614 0.88 CRHBP (0.43) CRHBPCRHR2DRD2DRD4TSHR
SCHEMBL11431616 0.88 CRHBP (0.43) CRHBPCRHR2DRD2DRD4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393787-B1 Electrophotographic recording material AGFA GEVAERT NV (BE) 1995-02-15 EP disclosed
EP-0347960-B1 Photosensitive recording material suited for use in electrophotography AGFA GEVAERT NV (BE) 1994-07-06 EP disclosed
US-5145759-A Conductive support, negatively chargeable photoconductive layer containing insulating polymeric binder with pigment and charge transport substance AGFA-GEVAERT, N.V. (BE) 1992-09-08 US disclosed
US-4981768-A Photosensitive recording material having an N-aryl carbazole p-type charge transport compound AGFA-GEVAERT, N.V. (BE) 1991-01-01 US disclosed
EP-0393787-A2 Electrophotographic recording material AGFA-GEVAERT N.V. (BE) 1990-10-24 EP disclosed
EP-0347960-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed
EP-0347967-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed