SCHEMBL3975558

SCHEMBL3975558

CCN1c2ccccc2C(C)CC1(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
DRD4 P21917 2/20 0.42
DRD2 P14416 1/20 0.42
TSHR P16473 1/20 0.40
MAPT P10636 6/20 0.38
ALDH1A1 P00352 4/20 0.38
LMNA P02545 3/20 0.38
GAA P10253 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
HTT P42858 2/20 0.38
MEN1 O00255 2/20 0.38
NOTUM Q6P988 1/20 0.38
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
MPI P34949 1/20 0.38
MCL1 Q07820 1/20 0.38
NPSR1 Q6W5P4 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9155272 0.88 CRHBP (0.48) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL11428861 0.87 CRHBP (0.45) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL9636461 0.84 CRHBP (0.43) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL10886763 0.83 CRHBP (0.43) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL8942349 0.83 CRHBP (0.47) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL11431643 0.83 CRHBP (0.44) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL11419734 0.83 CRHBP (0.47) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL11416787 0.83 CRHBP (0.44) CRHBPCRHR2DRD4DRD2TSHR
SCHEMBL9073520 0.83 AMPD2 (0.49) CRHBPCRHR2DRD4DRD2LMNA
SCHEMBL11420280 0.82 CRHBP (0.42) CRHBPCRHR2DRD4DRD2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59030861-A None JP disclosed
WO-2009047534-A2 FUSED PHENOTHIAZINIUM COMPOUNDS, PREPARATION METHOD THEREOF AND USE AS PHOTOANTIMICROBIALS PHARMALUCIA LTD (GB) 2009-04-16 WO disclosed
US-5578711-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-5541299-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-07-30 US disclosed
US-5502171-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed
EP-0446731-B1 Process for the manufacture of azo dyes BAYER AG (DE) 1995-05-03 EP disclosed
US-5233048-A Tert-aminearyl-imidazol-1-yl or 1,2,4-triazol-1-ly color materials; pressure sensitive recording materials; sublimation , light fastness BAYER AKTIENGESELLSCHAFT (DE) 1993-08-03 US disclosed
US-5189188-A Suitable as color formers in pressure-sensitive and thermo reactive dyes; photostability BAYER AKTIENGESELLSCHAFT (DE) 1993-02-23 US disclosed
EP-0237915-B1 CHROMOGENIC PHTHALIDES, THEIR PREPARATION AND USE BAYER AG (DE) 1992-05-13 EP disclosed
EP-0327063-B1 HEAT TRANSFER SHEET DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1992-04-22 EP disclosed
US-4529406-A Monoazo dye RESEARCH ASSOCIATION OF DYESTUFF MANUFACTURERS (JP) 1985-07-16 US disclosed
US-4525588-A FOR HEAT AND PRESSURE SENSITIVE RECORDING MATERIALS CIBA GEIGY CORPORATION (US) 1985-06-25 US disclosed
EP-0081125-B1 CATIONIC DYES, THEIR PREPARATION PROCESS AND THEIR USE IN DYEING AND MASS DYEING BAYER AG (DE) 1985-05-08 EP disclosed
EP-0102729-A1 Nitrothiazoleazo compounds, their preparation and use in dyeing synthetic fibers RESEARCH ASSOCIATION OF DYESTUFF MANUFACTURES (JP) 1984-03-14 EP disclosed
JP-S5930861-A MONOAZO COMPOUND AND DYEING METHOD USING THE SAME GOSEI SENRIYOU GIJUTSU KENKYU KUMIAI 1984-02-18 JP disclosed
EP-0081125-A1 Cationic dyes, their preparation process and their use in dyeing and mass dyeing BAYER AG (DE) 1983-06-15 EP disclosed
US-4185151-A 1-R-2-(U-HYDROXYALKYL-2,2,4-TRIMETHYL TETRAHYDROQUINOL-6-YL) BENZ(CD)INDOLES BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-4000141-A SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed
US-3998801-A MONOAZO DYES; POLYAMIDES; RED TO VIOLET SHADES EASTMAN KODAK COMPANY (US) 1976-12-21 US disclosed
US-3991042-A Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US disclosed