Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749901 | 0.84 | LMNA (0.54) | CES2CES1SMN1; SMN2LMNANAPRT | |
| SCHEMBL9466488 | 0.82 | LMNA (0.60) | CES2CES1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL29128035 | 0.80 | CES2 (0.50) | CES2CES1SMN1; SMN2LMNANAPRT | |
| SCHEMBL31366857 | 0.80 | CES2 (0.50) | CES2CES1SMN1; SMN2LMNANAPRT | |
| SCHEMBL27800461 | 0.79 | CES2 (0.45) | CES2CES1SMN1; SMN2LMNANAPRT | |
| SCHEMBL16245005 | 0.78 | CES2 (0.42) | CES2CES1SMN1; SMN2LMNANAPRT | |
| Hydrochloric Acid SCHEMBL17845878 | 0.78 | KDM4E (0.47) | CES2CES1SMN1; SMN2LMNANAPRT | |
| SCHEMBL29174093 | 0.77 | HDAC1 (0.41) | CES2CES1SMN1; SMN2LMNANAPRT | |
| Water SCHEMBL29152768 | 0.77 | CES2 (0.41) | CES2CES1SMN1; SMN2LMNANAPRT | |
| SCHEMBL6157036 | 0.76 | CES2 (0.50) | CES2CES1SMN1; SMN2LMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447942-A | Treatment of bronchoconstriction | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1995-09-05 | — | — | US | disclosed |