Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466488 | 0.95 | LMNA (0.60) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| Hydrochloric Acid SCHEMBL17845878 | 0.87 | KDM4E (0.47) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL9155331 | 0.84 | CES2 (0.44) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL472967 | 0.81 | ALDH1A1 (0.50) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| Bromide SCHEMBL27970014 | 0.79 | ALDH1A1 (0.48) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL16353921 | 0.79 | LMNA (0.54) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL1255008 | 0.79 | CTNNB1 (0.59) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL28831193 | 0.78 | SMN1; SMN2 (0.47) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL27800461 | 0.78 | CES2 (0.45) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL8606134 | 0.77 | LMNA (0.53) | LMNAKDM4EHTTSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2859023-B1 | NEUTRAL LAYER POLYMER COMPOSITION FOR DIRECTED SELF ASSEMBLY AND PROCESSES THEREOF | AZ ELECTRONIC MAT (LUXEMBOURG) S À R L (LU) | 2017-07-19 | — | — | EP | claimed |
| EP-0834777-B1 | Cationic toner processes | XEROX CORP (US) | 2001-01-03 | — | — | EP | claimed |
| WO-2019051585-A1 | CHIRAL CATALYST AND METHOD FOR ASYMMETRIC REDUCTION OF AN IMINE | DALHOUSIE UNIVERSITY (CA) | 2019-03-21 | — | — | WO | disclosed |