Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157349 | 0.92 | ALDH1A1 (0.44) | ALDH1A1HSD17B10GAATDP1MEN1 | |
| SCHEMBL9153633 | 0.89 | ALDH1A1 (0.47) | ALDH1A1GAATDP1MEN1NPC1 | |
| SCHEMBL9152750 | 0.86 | ALDH1A1 (0.46) | ALDH1A1GAATDP1MEN1NPC1 | |
| SCHEMBL9158369 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HSD17B10GAATDP1MEN1 | |
| SCHEMBL8860020 | 0.83 | ALDH1A1 (0.55) | ALDH1A1GAATDP1MEN1NPC1 | |
| SCHEMBL9153600 | 0.83 | ALDH1A1 (0.45) | ALDH1A1GAATDP1MEN1NPC1 | |
| SCHEMBL9154411 | 0.81 | GABRP (0.41) | ALDH1A1TSHRGLA | |
| SCHEMBL9154498 | 0.81 | ALDH1A1 (0.47) | ALDH1A1GAATDP1MEN1NPC1 | |
| SCHEMBL9132781 | 0.79 | RAB9A (0.42) | ALDH1A1GAATDP1NPC1RAB9A | |
| SCHEMBL9152697 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAATDP1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |