Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fantofarone SCHEMBL77818 | 0.93 | CYP3A4 (0.59) | KDM4ECYP3A4MAPTTP53TSHR | |
| Fantofarone SCHEMBL29802340 | 0.93 | CYP3A4 (0.59) | KDM4ECYP3A4MAPTTP53TSHR | |
| Fantofarone SCHEMBL9599714 | 0.92 | CYP3A4 (0.59) | KDM4ECYP3A4MAPTTP53TSHR | |
| SCHEMBL9598076 | 0.91 | CYP3A4 (0.57) | KDM4ECYP3A4MAPTTP53TSHR | |
| SCHEMBL9157509 | 0.87 | CYP3A4 (0.50) | KDM4ECYP3A4MAPTTP53TSHR | |
| Hydrochloric Acid SCHEMBL9655914 | 0.86 | CYP3A4 (0.49) | KDM4ECYP3A4MAPTTP53TSHR | |
| SCHEMBL9603542 | 0.85 | HTR6 (0.47) | KDM4ECYP3A4MAPTTP53TSHR | |
| SCHEMBL4162892 | 0.84 | MAPT (0.44) | KDM4ECYP3A4MAPTTP53TSHR | |
| SCHEMBL6451740 | 0.84 | MAPT (0.44) | KDM4ECYP3A4MAPTTP53TSHR | |
| SCHEMBL9215666 | 0.84 | KDM4E (0.48) | KDM4ECYP3A4MAPTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403933-A | Chemical intermediates for cardiotonic, hypotensive, antiarrhymia and bradycadial agents; cognition activators | ELF SANOFI (FR) | 1995-04-04 | — | — | US | disclosed |
| US-5182291-A | Angina pectoris, hypotensive, antiarrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |
| US-5039700-A | Cardiovascular disorders, antitumor agents | SANOFI (FR) | 1991-08-13 | — | — | US | disclosed |
| US-5017579-A | Use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure | SANOFI (FR) | 1991-05-21 | — | — | US | disclosed |
| US-4957925-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS, TREATMENT OF ANGINA | SANOFI (FR) | 1990-09-18 | — | — | US | disclosed |