Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157509 | 0.95 | CYP3A4 (0.50) | KDM4ETP53CYP3A4MAPTTSHR | |
| Hydrochloric Acid SCHEMBL9655914 | 0.95 | CYP3A4 (0.49) | KDM4ETP53CYP3A4MAPTTSHR | |
| Fantofarone SCHEMBL77818 | 0.89 | CYP3A4 (0.59) | KDM4ETP53CYP3A4MAPTTSHR | |
| Fantofarone SCHEMBL29802340 | 0.89 | CYP3A4 (0.59) | KDM4ETP53CYP3A4MAPTTSHR | |
| Fantofarone SCHEMBL9599714 | 0.89 | CYP3A4 (0.59) | KDM4ETP53CYP3A4MAPTTSHR | |
| SCHEMBL9656156 | 0.89 | KDM4E (0.46) | KDM4ETP53CYP3A4MAPTTSHR | |
| SCHEMBL9598076 | 0.87 | CYP3A4 (0.57) | KDM4ETP53CYP3A4MAPTTSHR | |
| Oxalic Acid SCHEMBL9267570 | 0.87 | KDM4E (0.44) | KDM4ETP53CYP3A4MAPTTSHR | |
| SCHEMBL9156142 | 0.84 | KDM4E (0.51) | KDM4ETP53CYP3A4MAPTTSHR | |
| Citric Acid SCHEMBL9264207 | 0.83 | KDM4E (0.41) | KDM4ETP53CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382618-B1 | Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them | SANOFI SA (FR) | 1995-09-20 | — | — | EP | claimed |
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |