Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432092 | 0.87 | ESR1 (0.46) | TDP1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL18899967 | 0.76 | ALDH1A1 (0.48) | TDP1MAPTALDH1A1CASP1KDM4E | |
| SCHEMBL8433818 | 0.76 | POLB (0.46) | TDP1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL8432173 | 0.75 | ESR1 (0.40) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23133350 | 0.75 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1CASP1KDM4E | |
| Potassium SCHEMBL8958438 | 0.75 | POLB (0.45) | TDP1MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL19175473 | 0.75 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1CASP1KDM4E | |
| SCHEMBL8433213 | 0.74 | ALDH1A1 (0.43) | TDP1MAPTALDH1A1CASP1KDM4E | |
| SCHEMBL8433342 | 0.74 | ALDH1A1 (0.47) | TDP1ALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL5067200 | 0.72 | SMN1; SMN2 (0.49) | TDP1MAPTALDH1A1CASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363034-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1995-01-04 | — | — | EP | disclosed |
| EP-0605404-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | disclosed |
| US-5212313-A | For polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-18 | — | — | US | disclosed |
| US-5183888-A | Reacting a phenyl tartronic acid with a dihydrobenzofuran, oxidizing, to get dihydrobenzodifuran | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |