Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158637 | 0.89 | MAOA (0.62) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL8352256 | 0.86 | MAOA (0.68) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Hydrocinnamyl Alcohol SCHEMBL28833914 | 0.85 | MAOA (0.62) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| 4-Phenyl-Butylamine SCHEMBL8103485 | 0.84 | MAOA (0.66) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| Propylamine SCHEMBL27818094 | 0.83 | HTR2A (0.64) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| 4-Phenyl-Butylamine SCHEMBL8353115 | 0.82 | MAOA (0.63) | MAOAHTR2A | |
| 4-Phenyl-Butylamine SCHEMBL8356098 | 0.82 | MAOA (0.63) | MAOAHTR2A | |
| Alcohol SCHEMBL25175233 | 0.81 | TDP1 (0.59) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| Hydrogen Peroxide SCHEMBL3918960 | 0.81 | TDP1 (0.57) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL8338201 | 0.80 | MAOA (0.72) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284621-B1 | NEW PSYCHOSTIMULANT AGENT | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1995-01-18 | — | — | EP | disclosed |
| EP-0284621-A1 | NEW PSYCHOSTIMULANT AGENT. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1988-10-05 | — | — | EP | disclosed |
| WO-1988002254-A1 | NEW PSYCHOSTIMULANT AGENT | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-04-07 | — | — | WO | disclosed |