Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160413 | 0.86 | KDM4E (0.46) | HTR1DHTR1BKDM4EGAAAR | |
| SCHEMBL9157725 | 0.81 | ALDH1A1 (0.46) | HTR1DKDM4EARALDH1A1HPGD | |
| SCHEMBL19737586 | 0.77 | LMNA (0.59) | KDM4EGAAARKIF11ALDH1A1 | |
| SCHEMBL9156288 | 0.76 | CNR1 (0.49) | HTR1DHTR1BKDM4EGAACNR1 | |
| SCHEMBL9154966 | 0.75 | ALDH1A1 (0.56) | KDM4EGAAALDH1A1HPGDTSHR | |
| SCHEMBL22643826 | 0.75 | AR (0.56) | HTR1DKDM4EGAAARKIF11 | |
| SCHEMBL10650676 | 0.74 | KDM4E (0.54) | KDM4EGAAARKIF11ALDH1A1 | |
| SCHEMBL38650847 | 0.74 | KDM4E (0.54) | KDM4EGAAARKIF11ALDH1A1 | |
| SCHEMBL9159477 | 0.73 | CA12 (0.51) | ALDH1A1NPSR1LMNA | |
| SCHEMBL9153152 | 0.72 | LMNA (0.42) | KDM4EGAAKIF11ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |