Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157725 | 0.88 | ALDH1A1 (0.46) | LMNAMAPTHTR2AMEN1KMT2A | |
| SCHEMBL9155186 | 0.84 | ALDH1A1 (0.45) | LMNAMAPTMITFHTR2AMEN1 | |
| SCHEMBL12667294 | 0.83 | MAPT (0.51) | LMNAMAPTHTR2AMEN1KMT2A | |
| SCHEMBL9156800 | 0.83 | METAP2 (0.42) | MAPTMEN1KMT2AHPGDKDM4E | |
| SCHEMBL9154966 | 0.79 | ALDH1A1 (0.56) | MITFMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2795205 | 0.76 | KDM4E (0.67) | LMNAALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL10919832 | 0.76 | HTR2A (0.71) | HTR2AMEN1KMT2A | |
| SCHEMBL9152233 | 0.75 | KDM4E (0.42) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8109985 | 0.75 | KDM4E (0.59) | LMNAMAPTMITFALDH1A1HPGD | |
| SCHEMBL4112149 | 0.74 | KDM4E (0.50) | LMNAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457099-A | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0577325-A1 | Carbostyril derivatives and antiallergic agent | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |