Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173917 | 0.95 | NAAA (0.56) | NAAACYP3A4TSHRTYRRECQL | |
| SCHEMBL9363845 | 0.82 | TLR8 (0.45) | NAAAHTTMAPTMEN1KMT2A | |
| SCHEMBL1161081 | 0.81 | IDO1 (0.49) | NAAACYP3A4TSHRHTTMAPT | |
| SCHEMBL9576022 | 0.80 | GAA (0.46) | TSHRRECQLHTTMAPTMEN1 | |
| SCHEMBL2901815 | 0.79 | PLK1 (0.46) | NAAATDP1ESR1ESR2 | |
| SCHEMBL9650900 | 0.79 | ABL1 (0.50) | NAAAALOX5PTGS2IDO1EGFR | |
| SCHEMBL1955524 | 0.78 | IDO1 (0.46) | NAAACYP3A4ALOX5PTGS2HTT | |
| SCHEMBL2398365 | 0.77 | CYP3A4 (0.64) | NAAACYP3A4TSHRTYRRECQL | |
| SCHEMBL29069494 | 0.77 | TRPA1 (0.48) | NAAAMAPTMEN1KMT2A | |
| SCHEMBL9645537 | 0.77 | NAAA (0.43) | NAAAHTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | claimed |
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | disclosed |