Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379429 | 0.83 | RAB9A (0.55) | ALDH1A1MAPK1KMT2ANPC1RAB9A | |
| SCHEMBL9160444 | 0.82 | NPC1 (0.46) | ALDH1A1MAPK1PTPN1NR4A2KMT2A | |
| SCHEMBL10886595 | 0.82 | KMT2A (0.50) | ALDH1A1TRPA1MAPK1GSK3BHIF1A | |
| SCHEMBL6500124 | 0.81 | NR4A2 (0.65) | NR4A2KMT2ANPC1RAB9ANR4A1 | |
| SCHEMBL7337987 | 0.80 | NR4A2 (0.72) | PTPN1NR4A2KMT2AMAOBMAOA | |
| SCHEMBL2379240 | 0.79 | CES2 (0.65) | ALDH1A1TRPA1MAPK1GSK3BHIF1A | |
| SCHEMBL8548986 | 0.78 | ERCC5 (0.67) | ALDH1A1TRPA1MAPK1GSK3BHIF1A | |
| SCHEMBL235381 | 0.77 | MAOB (0.48) | PTPN1NR4A2MAOBMAOANPC1 | |
| SCHEMBL883109 | 0.77 | TNKS (0.58) | ALDH1A1TRPA1MAPK1GSK3BHIF1A | |
| SCHEMBL8347604 | 0.77 | KMT2A (0.54) | ALDH1A1TRPA1MAPK1GSK3BHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639049-A1 | HALOGENATED 4'-METHOXYACETOPHENONES AS MICROBICIDES AND PRESERVATIVES | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| WO-1993022918-A1 | HALOGENATED 4'-METHOXYACETOPHENONES AS MICROBICIDES AND PRESERVATIVES | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1993-11-25 | — | — | WO | disclosed |