SCHEMBL9156940

SCHEMBL9156940

CCC(COC(=O)C(C)N1CC1)(COC(=O)C(C)N1CC1)COC(=O)C(C)N1CC1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2218448 0.85 SMN1; SMN2 (0.40) ALDH1A1
SCHEMBL31346719 0.79 SIGMAR1 (0.43)
SCHEMBL6129180 0.78 ALDH1A1 (0.46) ALDH1A1GAAPKMLMNAMAPT
SCHEMBL181261 0.77 SMN1; SMN2 (0.36) THRB
SCHEMBL11036817 0.76 MAPT (0.33) ALDH1A1GAAPKMKDM4ELMNA
SCHEMBL13346798 0.76 THRB (0.40) THRBALDH1A1MAPT
SCHEMBL29419952 0.75 ALDH1A1 (0.38) THRBALDH1A1GAAKDM4ELMNA
SCHEMBL14270893 0.74 THRB (0.39) THRBALDH1A1
SCHEMBL19196174 0.73 TP53 (0.33) ALDH1A1
SCHEMBL10028722 0.73 TP53 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436327-B1 Water- and oil-repellent treatment agent MINNESOTA MINING & MFG (US) 1995-02-01 EP claimed
EP-0438886-B1 Water- and oil-repellent treatment agent MINNESOTA MINING & MFG (US) 1994-02-02 EP claimed
US-5132028-A Fluoropolymer, especially for silk MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-21 US claimed
US-5084191-A Fibers with oil and water repellants of fluorochemicals, aziri dines and metal alcoholates or esters and drying MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-28 US claimed
EP-0438886-A1 Water- and oil-repellent treatment agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-31 EP claimed
EP-0436327-A1 Water- and oil-repellent treatment agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-10 EP claimed
EP-0436327-B1 Water- and oil-repellent treatment agent MINNESOTA MINING & MFG (US) 1995-02-01 EP disclosed
EP-0438886-B1 Water- and oil-repellent treatment agent MINNESOTA MINING & MFG (US) 1994-02-02 EP disclosed
US-5132028-A Fluoropolymer, especially for silk MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-21 US disclosed
US-5084191-A Fibers with oil and water repellants of fluorochemicals, aziri dines and metal alcoholates or esters and drying MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-28 US disclosed
EP-0438886-A1 Water- and oil-repellent treatment agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-31 EP disclosed
EP-0436327-A1 Water- and oil-repellent treatment agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-10 EP disclosed