Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SQLE | Q14534 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157291 | 1.00 | KMT2A (0.64) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL24092723 | 0.93 | KMT2A (0.77) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL18705403 | 0.93 | KMT2A (0.77) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL9159032 | 0.93 | KMT2A (0.77) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL9159020 | 0.93 | KMT2A (0.77) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL11167605 | 0.88 | HPGD (0.55) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL23888084 | 0.88 | KMT2A (0.68) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL9137864 | 0.88 | KMT2A (0.77) | KMT2ASQLEMAPTALDH1A1MEN1 | |
| SCHEMBL23888086 | 0.88 | KMT2A (0.68) | KMT2AHPGDSQLEMAPTALDH1A1 | |
| SCHEMBL14296529 | 0.88 | HPGD (0.55) | KMT2AHPGDSQLEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069417-A1 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | LY CORED LTD. (IL) | 2009-03-12 | — | — | US | disclosed |
| WO-2007043046-A2 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | LYCORED LTD. (IL) | 2007-04-19 | — | — | WO | disclosed |
| EP-0448934-B1 | Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase | MERRELL DOW PHARMA (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5157166-A | Condensing difluoromethyldiphenylphosphine oxide and a polyalkylpolyunsaturated docosanal to difluoromethenylate | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5064864-A | ANTICHOLESTEROL AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0448934-A2 | Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-02 | — | — | EP | disclosed |
| US-5011859-A | Anticholesterol agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069417-A1 | CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS | DOHH, BBOX1, TXN2 | KMT2A 1888/4885HPGD 417/4885SQLE 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.