Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGFR | P43088 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157538 | 1.00 | MAPT (0.52) | MAPTRAB9AKDM4ENPC1FKBP1A | |
| SCHEMBL7427668 | 0.88 | MAPT (0.48) | MAPTRAB9AKDM4ENPC1FKBP1A | |
| SCHEMBL7427677 | 0.88 | MAPT (0.48) | MAPTRAB9AKDM4ENPC1FKBP1A | |
| SCHEMBL10479627 | 0.76 | MAPT (0.57) | MAPTRAB9AKDM4ENPC1FKBP1A | |
| SCHEMBL6548977 | 0.75 | PLK1 (0.47) | MAPTRAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL6548980 | 0.75 | PLK1 (0.47) | MAPTRAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL8012913 | 0.75 | PTGER3 (0.61) | MAPTPTGER4PTGER3PTGER2TBXA2R | |
| SCHEMBL8012911 | 0.75 | PTGER3 (0.61) | MAPTPTGER4PTGER3PTGER2TBXA2R | |
| SCHEMBL11121684 | 0.75 | MAPT (0.56) | MAPTRAB9AKDM4ENPC1FKBP1A | |
| SCHEMBL4719668 | 0.75 | MGLL (0.68) | MAPTRAB9AKDM4ENPC1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466405-B1 | 2,2'-Bis(dicyclopenthylphosphino)-1-1'-binaphthyl and metal complexes thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-5312939-A | 2,2'-bis (dicyclopentylphosphino)-1,1'-binaphthyl and transition metal complex using the same as ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0466405-A1 | 2,2'-Bis(dicyclopenthylphosphino)-1-1'-binaphthyl and metal complexes thereof | Takasago International Corporation (JP) | 1992-01-15 | — | — | EP | disclosed |