Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277775 | 0.88 | ESR1 (0.43) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL25969208 | 0.83 | ESR1 (0.64) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL22199971 | 0.82 | CA9 (0.59) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL13819250 | 0.81 | CA9 (0.47) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL12352479 | 0.81 | ESR1 (0.56) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL13460950 | 0.80 | ESR1 (0.55) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL29906097 | 0.80 | ESR1 (0.55) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL25161435 | 0.80 | CA9 (0.71) | CA9CA1CA12CA2ALDH1A1 | |
| SCHEMBL9160469 | 0.80 | CA9 (0.50) | CA9CA1CA12CA2ESR1 | |
| SCHEMBL12260131 | 0.80 | ALDH1A1 (0.51) | CA9CA1CA12CA2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3068587-A | — | — | None | — | — | JP | disclosed |
| EP-0402632-B1 | Aromatic polyimide silanol compounds, precursors and polymers thereof | HUGHES AIRCRAFT CO (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5021585-A | Engineering thermoplastics; good optics, heat and oxidation resistance | HUGHES AIRCRAFT COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| JP-H0368587-A | AROMATIC POLYIMIDOSILANOL, ITS PRECURSOR AND POLYMER THEREOF | HUGHES AIRCRAFT CO | 1991-03-25 | — | — | JP | disclosed |
| EP-0402632-A2 | Aromatic polyimide silanol compounds, precursors and polymers thereof | Hughes Aircraft Company (US) | 1990-12-19 | — | — | EP | disclosed |