Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165974 | 0.79 | MAPT (0.37) | SMN1; SMN2KMT2ATDP1LMNAMAPT | |
| SCHEMBL9166485 | 0.78 | ALDH1A1 (0.35) | KMT2AHTTMAPTTP53 | |
| SCHEMBL9161861 | 0.77 | ALDH1A1 (0.31) | HTTMAPT | |
| SCHEMBL9164310 | 0.67 | KDM4E (0.37) | SMN1; SMN2KMT2AMEN1LMNARAB9A | |
| SCHEMBL23398832 | 0.64 | LMNA (0.35) | SMN1; SMN2KMT2ATDP1MEN1LMNA | |
| SCHEMBL1194986 | 0.64 | MAPK1 (0.45) | SMN1; SMN2TDP1LMNAHTTNPC1 | |
| SCHEMBL22286223 | 0.61 | HPGD (0.47) | SMN1; SMN2KMT2ATSHRMAPK1NPSR1 | |
| SCHEMBL9825854 | 0.59 | KMT2A (0.33) | KMT2A | |
| SCHEMBL21719161 | 0.59 | NPC1 (0.35) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL21721031 | 0.58 | TP53 (0.36) | SMN1; SMN2TDP1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442060-A | Treating hyperlipemia, atherosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0591830-A1 | Carboxamide and urea derivatives having ACAT-inhibiting activityM | Mitsubishi Chemical Corporation (JP) | 1994-04-13 | — | — | EP | disclosed |