Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162158 | 0.84 | LMNA (0.35) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9161861 | 0.82 | ALDH1A1 (0.31) | ALDH1A1MAPTHTT | |
| SCHEMBL9165974 | 0.81 | MAPT (0.37) | ALDH1A1MAPTKMT2AKDM4ETP53 | |
| SCHEMBL9157928 | 0.78 | SMN1; SMN2 (0.37) | MAPTHTTKMT2ATP53 | |
| SCHEMBL4360066 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL25434879 | 0.74 | KDM4E (0.41) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL31735452 | 0.74 | GAA (0.40) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL22574804 | 0.69 | MAPT (0.44) | ALDH1A1MAPTHTT | |
| SCHEMBL9164310 | 0.69 | KDM4E (0.37) | ALDH1A1MAPTKMT2AKDM4ETP53 | |
| SCHEMBL8271720 | 0.66 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442060-A | Treating hyperlipemia, atherosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0591830-A1 | Carboxamide and urea derivatives having ACAT-inhibiting activityM | Mitsubishi Chemical Corporation (JP) | 1994-04-13 | — | — | EP | disclosed |