Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028177 | 0.78 | LIPE (0.46) | CYP2C9ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9160768 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDKDM4EGAA | |
| SCHEMBL9160777 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDKDM4EGAA | |
| SCHEMBL15516069 | 0.75 | ALDH1A1 (0.44) | CYP2C9ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27914158 | 0.73 | ALDH1A1 (0.53) | CYP2C9ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9156623 | 0.72 | TSHR (0.30) | CYP2C19TSHRNFKB1 | |
| SCHEMBL838932 | 0.71 | CYP3A4 (0.45) | CYP2C9ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9955820 | 0.70 | ALDH1A1 (0.43) | CYP2C9ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1197047 | 0.70 | ALDH1A1 (0.43) | CYP2C9ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15540704 | 0.70 | ALDH1A1 (0.43) | CYP2C9ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |