Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160777 | 1.00 | ALDH1A1 (0.39) | ALDH1A1DPP7DPP4THRBRECQL | |
| SCHEMBL11761306 | 0.77 | ALDH1A1 (0.41) | ALDH1A1DPP7DPP4LMNAHPGD | |
| SCHEMBL9158034 | 0.77 | CYP2C9 (0.39) | ALDH1A1RECQLLMNAHPGDKDM4E | |
| SCHEMBL1077421 | 0.73 | HPGD (0.42) | ALDH1A1DPP7DPP4ATMHPGD | |
| SCHEMBL6608018 | 0.73 | ALDH1A1 (0.40) | ALDH1A1DPP7DPP4ATMHPGD | |
| SCHEMBL11687527 | 0.72 | DPP7 (0.48) | ALDH1A1DPP7LMNAHPGDKDM4E | |
| SCHEMBL3559523 | 0.72 | DPP7 (0.48) | ALDH1A1DPP7LMNAHPGDKDM4E | |
| SCHEMBL11060294 | 0.71 | ALDH1A1 (0.44) | ALDH1A1DPP7DPP4HPGDKMT2A | |
| SCHEMBL6263459 | 0.71 | ALDH1A1 (0.44) | ALDH1A1DPP7HPGDTSHRGAA | |
| SCHEMBL28812874 | 0.71 | ALDH1A1 (0.39) | ALDH1A1DPP7DPP4ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |