Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158357 | 1.00 | GAA (0.46) | GAALMNAHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9158379 | 0.83 | ALDH1A1 (0.44) | LMNAHPGDTSHRSMN1; SMN2MEN1 | |
| SCHEMBL31378269 | 0.80 | CTSL (0.49) | GAALMNAHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9158572 | 0.79 | GAA (0.50) | GAALMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL27459999 | 0.79 | ALDH1A1 (0.50) | GAALMNAHPGDTSHRSMN1; SMN2 | |
| SCHEMBL5511994 | 0.78 | CA12 (0.50) | GAALMNAHPGDTSHRSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6567389 | 0.76 | CTSL (0.43) | GAALMNAHPGDTSHRSMN1; SMN2 | |
| SCHEMBL31262880 | 0.74 | CTSL (0.50) | GAALMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL31262932 | 0.73 | CTSL (0.49) | GAALMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL3307077 | 0.71 | ALDH1A1 (0.53) | GAALMNAHPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |