Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31378269 | 0.91 | CTSL (0.49) | CTSLCTSBCTSKDPP4ALDH1A1 | |
| SCHEMBL27459999 | 0.90 | ALDH1A1 (0.50) | CTSLCTSBCTSKALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL9551619 | 0.77 | ACE (0.47) | DPP4HTTDPP8LMNA | |
| SCHEMBL9155829 | 0.77 | ALDH1A1 (0.45) | CTSLCTSBCTSKALDH1A1HTT | |
| SCHEMBL9158363 | 0.76 | GAA (0.46) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL9158357 | 0.76 | GAA (0.46) | CTSLCTSBCTSKALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL18050103 | 0.75 | KMT2A (0.59) | ALDH1A1HTTLMNAMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5891447 | 0.74 | F10 (0.46) | MEN1KMT2A | |
| SCHEMBL31262880 | 0.73 | CTSL (0.50) | CTSLCTSBCTSKDPP4ALDH1A1 | |
| SCHEMBL31262932 | 0.72 | CTSL (0.49) | CTSLCTSBCTSKDPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401810-A1 | COMPOUNDS HAVING PROLYL OLIGOPEPTIDASE INHIBITORY ACTIVITY, METHODS FOR THEIR PREPARATION AND THEIR USE | ORION CORPORATION (FI) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003004468-A1 | COMPOUNDS HAVING PROLYL OLIGOPEPTIDASE INHIBITORY ACTIVITY, METHODS FOR THEIR PREPARATION AND THEIR USE | ORION CORPORATION (FI) | 2003-01-16 | — | — | WO | disclosed |