Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319296 | 0.96 | MAPT (0.54) | NFKB1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9158692 | 0.95 | MAPT (0.49) | NFKB1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL594105 | 0.91 | RAB9A (0.51) | NFKB1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9766627 | 0.89 | MAPT (0.43) | NFKB1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9850747 | 0.89 | MAPT (0.54) | NFKB1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL21469023 | 0.89 | MAPT (0.54) | NFKB1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9157673 | 0.89 | ALDH1A1 (0.46) | MAPTL3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL9158938 | 0.86 | RAB9A (0.50) | MAPTL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL9153756 | 0.86 | RARB (0.47) | NFKB1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9159976 | 0.85 | MAPT (0.49) | MAPTL3MBTL1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |