Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157673 | 0.88 | ALDH1A1 (0.46) | MAPTL3MBTL1RAB9AALDH1A1GAA | |
| SCHEMBL31119455 | 0.87 | — | — | |
| SCHEMBL91385 | 0.87 | — | — | |
| SCHEMBL9766627 | 0.86 | MAPT (0.43) | MAPTL3MBTL1RAB9AALDH1A1GAA | |
| SCHEMBL9158922 | 0.85 | NFKB1 (0.51) | MAPTL3MBTL1RAB9AALDH1A1GAA | |
| SCHEMBL6788044 | 0.83 | ALDH1A1 (0.49) | MAPTL3MBTL1RAB9AALDH1A1GAA | |
| SCHEMBL9158692 | 0.83 | MAPT (0.49) | MAPTL3MBTL1RAB9AALDH1A1GAA | |
| SCHEMBL9154338 | 0.82 | RAB9A (0.50) | MAPTL3MBTL1RAB9AALDH1A1KDM4E | |
| SCHEMBL9319296 | 0.80 | MAPT (0.54) | MAPTL3MBTL1RAB9AALDH1A1GAA | |
| SCHEMBL9154057 | 0.80 | PIK3CD (0.52) | MAPTL3MBTL1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |