Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159164 | 1.00 | MAPT (0.51) | MAPTNPC1RAB9AL3MBTL1MAPK1 | |
| SCHEMBL845803 | 0.83 | ALDH1A1 (0.56) | MAPTL3MBTL1GAAALDH1A1MEN1 | |
| SCHEMBL3350583 | 0.79 | ALDH1A1 (0.48) | MAPTL3MBTL1GAAALDH1A1MEN1 | |
| SCHEMBL14415144 | 0.77 | ALDH1A1 (0.46) | MAPTNPC1RAB9AL3MBTL1MAPK1 | |
| SCHEMBL4934508 | 0.77 | ACHE (0.58) | MAPTL3MBTL1GAAALDH1A1MEN1 | |
| SCHEMBL846838 | 0.76 | MAPT (0.51) | MAPTL3MBTL1GAAALDH1A1MEN1 | |
| SCHEMBL13170391 | 0.76 | ACHE (0.48) | MAPTL3MBTL1MAPK1GAAALDH1A1 | |
| SCHEMBL13093542 | 0.74 | MAPT (0.44) | MAPTNPC1RAB9AL3MBTL1MAPK1 | |
| SCHEMBL13085874 | 0.74 | MAPT (0.44) | MAPTNPC1RAB9AL3MBTL1MAPK1 | |
| SCHEMBL847263 | 0.74 | PDK1 (0.50) | MAPTNPC1RAB9AL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654696-A1 | Optical article containing a polymer that exhibits nonlinear second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5381507-A | Addition or condensation polymer containing oscillating molecular dipoles, perfluoroalkyl sulfonyl groups | EASTMAN KODAK COMPANY (US) | 1995-01-10 | — | — | US | disclosed |