Butane

Butane

SCHEMBL9159352

CCCC.N#Cc1ccc(O[PH](=O)O)cc1

nearest known ligand 0.47

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.47
ALDH1A1 P00352 2/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 1/20 0.42
CYP2A6 P11509 1/20 0.41
PGR P06401 4/20 0.41
MMP2 P08253 2/20 0.41
PARP15 Q460N3 1/20 0.40
PARP10 Q53GL7 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
HPGD P15428 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
HRH3 Q9Y5N1 1/20 0.39
MMP3 P08254 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL1339345 0.78 CA1 (0.44) PARP10PARP2CA1CA2CA9
SCHEMBL17061036 0.76 NQO1 (0.58) ALDH1A1PARP10CA1CA2CA9
Butane SCHEMBL976220 0.76 LTA4H (0.38)
SCHEMBL15849787 0.74 MEN1 (0.30)
Butane SCHEMBL4325616 0.74 SMN1; SMN2 (0.46) ALDH1A1MAPTRAB9AHPGDMAOB
Butane SCHEMBL8387084 0.72 CHRNB2 (0.41) ALDH1A1
SCHEMBL18037094 0.72 SMN1; SMN2 (0.47) ALDH1A1MAPTRAB9AHPGDMAOB
Butane SCHEMBL11055059 0.71 CA1 (0.55) MGLLALDH1A1MAPTRAB9AKDM4E
SCHEMBL995067 0.71 KIF11 (0.41) MGLLALDH1A1MAPTRAB9ACYP2A6
SCHEMBL3402078 0.71 SMN1; SMN2 (0.46) ALDH1A1MAPTRAB9AHPGDMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350113-B1 Liquid crystalline polyesters AKZO NOBEL NV (NL) 1995-01-25 EP disclosed
EP-0350112-B1 POLYURETHANES PREPARED FROM NON-LINEAR OPTICAL ACTIVE DIOLS Akzo Nobel N.V. (NL) 1993-10-06 EP disclosed
US-5001209-A Non-linear optical active diols and polyurethanes prepared therefrom AKZO N.V. (NL) 1991-03-19 US disclosed
US-4959448-A Optical waveguides AKZO N.V. (NL) 1990-09-25 US disclosed
EP-0350112-A1 Polyurethanes prepared from non-linear optical active diols Akzo Nobel N.V. (NL) 1990-01-10 EP disclosed
EP-0350113-A1 Liquid crystalline polyesters Akzo Nobel N.V. (NL) 1990-01-10 EP disclosed