Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17512952 | 0.83 | CA1 (0.55) | TSHRMAPTALDH1A1CYP2A6CA1 | |
| SCHEMBL27911911 | 0.81 | TSHR (0.48) | TSHRCYP2A6RAB9AMAOBL3MBTL1 | |
| SCHEMBL1339347 | 0.80 | TSHR (0.50) | TSHRMAPTALDH1A1CA1CA2 | |
| SCHEMBL25299492 | 0.78 | TSHR (0.48) | TSHRALDH1A1CA1CA2BCHE | |
| SCHEMBL649963 | 0.78 | TSHR (0.52) | TSHRCA1CA2ACHECCNT1 | |
| SCHEMBL578310 | 0.77 | CYP2A6 (0.50) | TSHRALDH1A1CYP2A6CCNT1CDK9 | |
| SCHEMBL24066284 | 0.77 | ALDH1A1 (0.50) | TSHRMAPTALDH1A1CYP2A6CA1 | |
| SCHEMBL28858781 | 0.75 | TSHR (0.45) | TSHRALDH1A1CA1CA2BCHE | |
| SCHEMBL4325620 | 0.75 | TSHR (0.45) | TSHRMAPTALDH1A1CA1CA2 | |
| SCHEMBL11682766 | 0.75 | MGLL (0.37) | MAPTALDH1A1CA1CA2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350113-B1 | Liquid crystalline polyesters | AKZO NOBEL NV (NL) | 1995-01-25 | — | — | EP | disclosed |
| EP-0350112-B1 | POLYURETHANES PREPARED FROM NON-LINEAR OPTICAL ACTIVE DIOLS | Akzo Nobel N.V. (NL) | 1993-10-06 | — | — | EP | disclosed |
| US-5001209-A | Non-linear optical active diols and polyurethanes prepared therefrom | AKZO N.V. (NL) | 1991-03-19 | — | — | US | disclosed |
| US-4959448-A | Optical waveguides | AKZO N.V. (NL) | 1990-09-25 | — | — | US | disclosed |
| EP-0350112-A1 | Polyurethanes prepared from non-linear optical active diols | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |
| EP-0350113-A1 | Liquid crystalline polyesters | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |