SCHEMBL17512952

SCHEMBL17512952

CCOP(=O)(OCC)Oc1ccc(C#N)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
BCHE P06276 1/20 0.55
ACHE P22303 1/20 0.55
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
MGLL Q99685 2/20 0.43
RAB9A P51151 1/20 0.43
TSHR P16473 2/20 0.41
CYP2A6 P11509 1/20 0.41
CYP3A4 P08684 1/20 0.41
PARP15 Q460N3 1/20 0.40
PARP10 Q53GL7 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
PGR P06401 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5026807 0.85 CA2 (0.70) CA1CA2BCHEACHEALDH1A1
SCHEMBL9159355 0.83 TSHR (0.48) CA1CA2BCHEACHEALDH1A1
SCHEMBL572710 0.83 TSHR (0.52) CA1CA2ALDH1A1MAPTMEN1
SCHEMBL31429667 0.83 CA2 (0.55) CA1CA2BCHEACHEMEN1
SCHEMBL28496394 0.81 MEN1 (0.44) CA1CA2BCHEACHEMEN1
Cyanophos-Oxon SCHEMBL17445283 0.80 CYP3A4 (0.45) CA1CA2ALDH1A1MAPTMEN1
SCHEMBL24066284 0.79 ALDH1A1 (0.50) CA1ALDH1A1MAPTPOLBMGLL
SCHEMBL20582535 0.79 CA2 (0.51) CA1CA2BCHEACHEALDH1A1
SCHEMBL20710745 0.78 CA1 (0.62) CA1CA2BCHEACHEMAPT
SCHEMBL3294100 0.78 TSHR (0.69) CA1CA2BCHEACHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417794-B Photochromic cellulose and preparation method thereof 中山大学 2020-04-24 CN claimed
CN-107163080-B Stimulus-responsive triphenylene photochromic material and synthesis method and application thereof 中山大学 2020-08-25 CN disclosed
CN-107417794-B Photochromic cellulose and preparation method thereof 中山大学 2020-04-24 CN disclosed
US-9660295-B2 Electrolyte and rechargeable lithium battery including the same SAMSUNG SDI CO., LTD. (KR) 2017-05-23 US disclosed
US-20160056505-A1 ELECTROLYTE AND RECHARGEABLE LITHIUM BATTERY INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2016-02-25 US disclosed