Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156180 | 0.91 | EPHX2 (0.43) | EPHX2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9471547 | 0.91 | ALDH1A1 (0.50) | EPHX2RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL9158371 | 0.90 | RAB9A (0.51) | EPHX2RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL9156431 | 0.89 | EPHX2 (0.43) | EPHX2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9159990 | 0.88 | ALDH1A1 (0.44) | EPHX2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9155538 | 0.87 | ALDH1A1 (0.42) | EPHX2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9159792 | 0.85 | EPHX2 (0.50) | EPHX2KMT2AMEN1THRBPKM | |
| SCHEMBL8036507 | 0.85 | RECQL (0.43) | RAB9ANPC1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL9252487 | 0.83 | MEN1 (0.41) | EPHX2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9157517 | 0.82 | MEN1 (0.51) | RAB9ANPC1SMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |