Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471547 | 0.91 | ALDH1A1 (0.50) | EPHX2CCKBRMEN1KMT2ATHRB | |
| SCHEMBL9158371 | 0.90 | RAB9A (0.51) | EPHX2CCKBRMEN1KMT2ATHRB | |
| SCHEMBL9158694 | 0.89 | KMT2A (0.41) | EPHX2FAAHDCUN1D1CCKBRKCNJ6 | |
| SCHEMBL9156180 | 0.87 | EPHX2 (0.43) | EPHX2FAAHDCUN1D1LMNAKCNJ6 | |
| SCHEMBL9159409 | 0.85 | EPHX2 (0.42) | EPHX2DCUN1D1LMNAKCNJ6KCNJ3 | |
| SCHEMBL9156842 | 0.85 | DCUN1D1 (0.42) | EPHX2DCUN1D1KCNJ6KCNJ3KCNJ5 | |
| SCHEMBL9156835 | 0.85 | DCUN1D1 (0.42) | EPHX2DCUN1D1KCNJ6KCNJ3KCNJ5 | |
| SCHEMBL9162155 | 0.85 | CCKBR (0.44) | EPHX2DCUN1D1CCKBRMEN1KMT2A | |
| SCHEMBL9162161 | 0.85 | CCKBR (0.44) | EPHX2DCUN1D1CCKBRMEN1KMT2A | |
| SCHEMBL9158560 | 0.85 | MEN1 (0.46) | EPHX2DCUN1D1CCKBRKCNJ6KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |