Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 4/20 | 0.55 |
| ▸ | FEN1 | P39748 | 7/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28709077 | 0.83 | FEN1 (0.42) | ALDH1A1L3MBTL1IDO1FEN1ALOX5AP | |
| SCHEMBL5342171 | 0.81 | ALOX5AP (0.49) | ALDH1A1L3MBTL1IDO1FEN1ALOX5AP | |
| SCHEMBL1062978 | 0.79 | CYP11B1 (0.47) | ALDH1A1L3MBTL1IDO1FEN1ALOX5AP | |
| SCHEMBL31114399 | 0.79 | CCR1 (0.56) | ALDH1A1L3MBTL1IDO1FEN1ALOX5AP | |
| SCHEMBL15006447 | 0.79 | CCR1 (0.56) | ALDH1A1L3MBTL1IDO1FEN1ALOX5AP | |
| SCHEMBL6291686 | 0.79 | NPC1 (0.53) | ALDH1A1L3MBTL1IDO1HSD17B10KDM4E | |
| SCHEMBL31114208 | 0.79 | CYP11B1 (0.47) | ALDH1A1L3MBTL1IDO1FEN1ALOX5AP | |
| SCHEMBL29450625 | 0.76 | KDM4E (0.56) | ALDH1A1L3MBTL1IDO1HSD17B10KDM4E | |
| SCHEMBL819951 | 0.76 | KDM4E (0.56) | ALDH1A1L3MBTL1IDO1HSD17B10KDM4E | |
| SCHEMBL13056712 | 0.75 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1IDO1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2887413-A1 | Use of compounds comprising a piperazine structural element in organic electronic devices and compounds and polymers comprising a piperazine structural element | Solvay SA (BE) | 2015-06-24 | — | — | EP | disclosed |
| US-5459266-A | Hydroxyphenyl-substituted as monomers for polyesters, polyaryl ates, polyether ketones, polycarbonates, polyepoxides | HOECHST CELANESE CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| US-5430123-A | Polymer compositions containing substituted pyrazines | HOECHST CELANESE CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5393860-A | Functional monomers for high performance polymers | HOECHST CELANESE CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |