Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | ATG7 | O95352 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607693 | 0.83 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL1445372 | 0.83 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL6454601 | 0.83 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL7608078 | 0.83 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL1445371 | 0.83 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL2108067 | 0.81 | CREBBP (0.36) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL2108607 | 0.79 | ALOX5 (0.44) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL2109207 | 0.75 | ALOX5 (0.49) | ALOX5TRIM24 | |
| SCHEMBL2107548 | 0.73 | ALOX5 (0.43) | ALOX5TRIM24 | |
| SCHEMBL8558044 | 0.73 | ALOX5 (0.48) | ALOX5TRIM24CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478842-A | Antiinflammatory agents, antiallergens, drugs for treatment of diseases mediated by leukotrienes | ZENECA LIMITED (GB) | 1995-12-26 | — | — | US | disclosed |